For those driving from other parts of Panama, the road conditions leading to Bocas Town can be challenging. The roads are mostly paved, but the final stretch from the mainland to the port of Almirante, where ferries depart for the islands, can be rough and prone to flooding during the rainy season. From Almirante, a scenic ferry ride brings travelers to Bocas Town.

Once in Bocas Town, travelers have the option to rent a car or book a private transfer service to get around. Renting a car provides the freedom to explore the islands at one's own pace, but travelers should be aware that road signs are scarce, and some roads can be narrow and unpaved. On the other hand, private transfer services offer a hassle-free experience, with drivers familiar with the area and its unique challenges. However, this option can be more expensive, especially for solo travelers or small groups.

It is highly recommended that travelers book their transportation services, including ferry tickets and private transfers, in advance, especially during peak season (December to April). This ensures availability and avoids last-minute hassles, allowing travelers to focus on enjoying their time in Bocas Town.